Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745365 | 0.78 | TSHR (0.38) | CTSBCYP3A4LMNA | |
| SCHEMBL6047877 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL6047875 | 0.77 | TDP1 (0.41) | PDE7AALDH1A1 | |
| SCHEMBL6047866 | 0.77 | ALDH1A1 (0.40) | PDE7AALDH1A1CYP3A4LMNA | |
| SCHEMBL25282743 | 0.75 | TDP1 (0.34) | ALDH1A1CYP2D6 | |
| SCHEMBL6047841 | 0.74 | MAPT (0.41) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL6047843 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL11884646 | 0.71 | — | — | |
| SCHEMBL9300521 | 0.70 | TDP1 (0.34) | PDE7AALDH1A1CYP2D6CTSBCYP3A4 | |
| SCHEMBL6047870 | 0.70 | ALDH3A1 (0.45) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |