Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27663441 | 0.84 | CTSS (0.57) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6048146 | 0.81 | CTSS (0.50) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5526308 | 0.80 | CTSS (0.49) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5519484 | 0.80 | CTSS (0.49) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5517731 | 0.80 | CTSS (0.49) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5422852 | 0.78 | CTSS (0.52) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL14378197 | 0.78 | CTSS (0.51) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL14378277 | 0.78 | CTSS (0.51) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6466909 | 0.76 | DAGLA (0.56) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL6466589 | 0.76 | DAGLA (0.56) | CTSSCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |