Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25210564 | 0.81 | MAP4K4 (0.46) | KDM4EMAPTMAPK14MAP4K4METAP2 | |
| SCHEMBL1494487 | 0.79 | IDO1 (0.47) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL13946985 | 0.78 | PARP1 (0.45) | IDO1KDM4EMAPTAURKAMAP4K4 | |
| SCHEMBL30014823 | 0.75 | IDO1 (0.56) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL12491361 | 0.73 | CYP3A4 (0.64) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL224770 | 0.72 | KDM4E (1.00) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL21631818 | 0.72 | MAPK14 (0.80) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL28163166 | 0.71 | KDM4E (0.56) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| Bromide SCHEMBL31020961 | 0.71 | KDM4E (0.96) | IDO1KDM4ECYP3A4MAPTMAPK14 | |
| SCHEMBL1501876 | 0.69 | METAP2 (0.50) | KDM4EMAPTMAP4K4METAP2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420037-B1 | Ion conducting membrane for electrochemical applications | GEESTHACHT GKSS FORSCHUNG (DE) | 2006-03-01 | — | — | EP | claimed |
| EP-1420037-A1 | Ion conducting membrane for electrochemical applications | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2004-05-19 | — | — | EP | claimed |
| EP-1420037-B1 | Ion conducting membrane for electrochemical applications | GEESTHACHT GKSS FORSCHUNG (DE) | 2006-03-01 | — | — | EP | disclosed |
| US-6869715-B2 | Ion conductive membrane for electrochemical application | GKSS-FORSCHUNGSZENTRUM GEESTHACHT, GMBH (DE) | 2005-03-22 | — | — | US | disclosed |
| US-20040101732-A1 | Ion conductive membrane for electrochemical application | GKSS FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
| EP-1420037-A1 | Ion conducting membrane for electrochemical applications | GKSS-FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |