Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1E | P28566 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6770600 | 0.99 | HTR7 (0.53) | HTR7HTR2ATAAR1DRD2HTR1A | |
| SCHEMBL6048513 | 0.87 | HTR7 (0.55) | HTR7HTR2ATAAR1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL6048617 | 0.86 | HTR7 (0.54) | HTR7HTR2ATAAR1DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL6048488 | 0.86 | HTR7 (0.54) | HTR7HTR2ATAAR1DRD2HTR1A | |
| SCHEMBL2096587 | 0.82 | ABCB1 (0.44) | HTR7MEN1KMT2A | |
| SCHEMBL23638842 | 0.81 | ABCB1 (0.61) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30451526 | 0.81 | ABCB1 (0.61) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9289360 | 0.80 | L3MBTL1 (0.50) | HTR7MEN1KMT2A | |
| SCHEMBL6048510 | 0.79 | HTR2A (0.56) | HTR7HTR2ATAAR1HTR1AHTR1D | |
| SCHEMBL5306327 | 0.79 | TAAR1 (0.46) | TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202953-B1 | SUBSTITUTED 2-DIALKYLAMINOALKYLBIPHENYL DERIVATIVES | GRUENENTHAL GMBH (DE) | 2006-08-30 | — | — | EP | claimed |
| US-6710080-B2 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20020198251-A1 | Substituted 2-dialkylaminoalkylbiphenyl derivatives | GRUENENTHAL GMBH (DE) | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198251-A1 | Substituted 2-dialkylaminoalkylbiphenyl derivatives | LIPA, PKD1, PKD2 | HTR7 501/4885HTR2A 615/4885TAAR1 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.