SCHEMBL6048566

SCHEMBL6048566

NP(=O)(OP(=O)(O)O)OP(=O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.60
BLM P54132 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CA4 P22748 1/20 0.38
BTN3A1 O00481 2/20 0.31
INPPL1 O15357 2/20 0.30
INPP5A Q14642 2/20 0.30
SMPD1 P17405 1/20 0.30
INPP5B P32019 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30192750 0.91 FDPS (0.50) FDPSBLMTDP1CA4
Pyrophosphoric Acid SCHEMBL28647299 0.81 FDPS (0.77) FDPSBLMTDP1CA4BTN3A1
Pyrophosphoric Acid SCHEMBL503971 0.81 FDPS (0.77) FDPSBLMTDP1CA4BTN3A1
SCHEMBL27355305 0.79 FDPS (0.41) FDPSBLMTDP1CA4
SCHEMBL1576918 0.79
SCHEMBL3191083 0.79
Pyrophosphoric Acid SCHEMBL8416891 0.77 FDPS (0.83) FDPSBLMTDP1CA4BTN3A1
Pyrophosphoric Acid SCHEMBL27805716 0.77 FDPS (0.83) FDPSBLMTDP1CA4BTN3A1
Pyrophosphoric Acid SCHEMBL10770702 0.77 FDPS (0.83) FDPSBLMTDP1CA4BTN3A1
Pyrophosphoric Acid SCHEMBL3654 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110168080-B Methods of detecting AAV 建新公司 2024-05-31 CN disclosed
CN-118028318-A Optimized CYP4V2 gene and application thereof 苏州诺洁贝生物技术有限公司 2024-05-14 CN disclosed
CN-111356763-B Variant RNAi 建新公司 2024-03-12 CN disclosed
CN-115896135-B Optimized PAH gene and expression cassette and use thereof 苏州诺洁贝生物技术有限公司 2024-03-01 CN disclosed
CN-117460832-A Size exclusion chromatography of empty AAV capsids and intact AAV capsids 建新公司 2024-01-26 CN disclosed
CN-114381465-B Optimized CYP4V2 gene and application thereof 苏州诺洁贝生物技术有限公司 2024-01-16 CN disclosed
CN-117085113-A TMEM25 protein and application thereof in cancer treatment 厦门大学 2023-11-21 CN disclosed
CN-116940372-A Haemophilus influenzae vaccine and methods of use 罗切斯特综合医院 2023-10-24 CN disclosed
CN-116801719-A Formulations for cryopreservation of PBMC SQZ生物技术公司 2023-09-22 CN disclosed
CN-116648503-A Human PAH expression cassettes for treatment of PKU by liver-directed gene replacement therapy 建新公司 2023-08-25 CN disclosed
US-6030813-A CHAIN EXTENSION BY ANNEALING PRIMER CONTAINING N3'-PHOSPHORAMIDATE AND PHOSPHODIESTER LINKAGES TO A POLYNUCLEOTIDE TEMPATE, THEN JOINING A NUCLEOTIDE TO THE PRIMER BY A POLYMERASE CATALYZED REACTION THE PERKIN-ELMAR CORPORATION (US) 2000-02-29 US disclosed
US-5965720-A WITH SEQUENCE COMPLEMENTARY TO MESSENGER RNA FROM A GENE SELECTED FROM THE GROUP CONSISTING OF C-MYC, C-MYB, C-FOS, C-KIT, RAS AND BCR/ABL; ANTISENSE/ANTICARCINOGENIC AGENTS LYNX THERAPEUTICS, INC. (US) 1999-10-12 US disclosed
US-5837835-A STABILITY; HEAT RESISTANCE LYNX THERAPEUTICS, INC. (US) 1998-11-17 US disclosed
US-5726297-A Oligodeoxyribonucleotide N3' P5' phosphoramidates LYNX THERAPEUTICS, INC. (US) 1998-03-10 US disclosed
EP-0754242-A4 OLIGONUCLEOTIDE N3'-m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES LYNX THERAPEUTICS INC (US) 1997-06-11 EP disclosed
US-5631135-A HYBRIDIZATION OF RIBONUCLEIC ACID TARGET; GENETIC ENGINEERING LYNX THERAPEUTICS, INC. (US) 1997-05-20 US disclosed
US-5599922-A INHIBITOR TO SNAKE VENON PHOSPHODIESTERASE LYNX THERAPEUTICS, INC. (US) 1997-02-04 US disclosed
EP-0754242-A1 OLIGONUCLEOTIDE N3'$m(7)P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES LYNX THERAPEUTICS, INC. (US) 1997-01-22 EP disclosed
US-5591607-A Oligonucleotide N3→P5' phosphoramidates: triplex DNA formation LYNX THERAPEUTICS, INC. (US) 1997-01-07 US disclosed
WO-1995025814-A1 OLIGONUCLEOTIDE N3'→P5' PHOSPHORAMIDATES: SYNTHESIS AND COMPOUNDS; HYBRIDIZATION AND NUCLEASE RESISTANCE PROPERTIES LYNX THERAPEUTICS, INC. (US) 1995-09-28 WO disclosed