SCHEMBL6048822

SCHEMBL6048822

CCCC[Si](Cl)(OCC)OCC

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048774 0.92 TSHR (0.33) TSHR
SCHEMBL6048696 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL26000123 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL30001823 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL6048703 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL6048682 0.90 TSHR (0.38) TSHRLMNA
SCHEMBL18107980 0.88 LMNA (0.31) LMNA
SCHEMBL6048922 0.83
SCHEMBL6064448 0.83
SCHEMBL18108348 0.82 ADRB2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7005399-B2 Catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2006-02-28 US claimed
EP-1270604-A1 CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2003-01-02 EP claimed
US-20020193244-A1 Catalyst for olefin polymerization TOHO TITANIUM CO., LTD. (JP) 2002-12-19 US claimed
EP-2658877-B1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORP (JP) 2023-04-12 EP disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 US disclosed
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-9499683-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2016-11-22 US disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
US-20140031471-A1 Stabilization Of Polymers That Contain A Hydrolyzable Functionality BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
EP-2658877-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY Bridgestone Corporation (JP) 2013-11-06 EP disclosed
WO-2012092626-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2012-07-05 WO disclosed
US-7141634-B2 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2006-11-28 US disclosed
US-7005399-B2 Catalyst for polymerization of olefins TOHO TITANIUM CO., LTD. (JP) 2006-02-28 US disclosed
US-20050250918-A1 Catalyst for olefin polymerization and process for polymerizing olefins TOHO CATALYST CO., LTD. (JP) 2005-11-10 US disclosed
EP-1270604-A1 CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2003-01-02 EP disclosed
US-20020193244-A1 Catalyst for olefin polymerization TOHO TITANIUM CO., LTD. (JP) 2002-12-19 US disclosed