SCHEMBL6048867

SCHEMBL6048867

CCOC(C)OCC.NCC(O)CO

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
HTT P42858 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.31
USP2 O75604 1/20 0.31
GABRR1 P24046 1/20 0.30
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL252728 0.86 LMNA (0.63) LMNAALDH1A1TDP1THRBUSP2
Glycerin SCHEMBL15655032 0.84 LMNA (0.60) LMNAALDH1A1TDP1THRBUSP2
Glycerin SCHEMBL5666737 0.80 LMNA (0.55) LMNAALDH1A1TDP1THRBUSP2
Ether SCHEMBL9588594 0.79 HTT (0.41) LMNAHTTALDH1A1THRBUSP2
Propylene Glycol SCHEMBL118981 0.79 LMNA (0.67) LMNAALDH1A1TDP1THRBTSHR
Alcohol SCHEMBL29055952 0.78
Glycerin SCHEMBL1579919 0.77 LMNA (0.50) LMNAALDH1A1TDP1
SCHEMBL8356847 0.76 TDP1 (0.50) LMNAALDH1A1TDP1THRBGABRR1
Hydroxyamine SCHEMBL7122122 0.75 LMNA (0.80) LMNAALDH1A1TDP1THRBTSHR
Isopropyl Alcohol SCHEMBL5499438 0.75 LMNA (0.80) LMNAALDH1A1TDP1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1331218-B1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof UNIV MICHIGAN STATE (US) 2006-12-27 EP claimed
EP-1084099-B1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF UNIV MICHIGAN STATE (US) 2003-03-26 EP claimed
EP-1084099-A4 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF UNIV MICHIGAN STATE (US) 2001-07-25 EP claimed
EP-1084099-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 2001-03-21 EP claimed
US-6040464-A Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-03-21 US claimed
WO-1999062861-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 1999-12-09 WO claimed
EP-1331218-B1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof UNIV MICHIGAN STATE (US) 2006-12-27 EP disclosed
EP-1331218-B1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof UNIV MICHIGAN STATE (US) 2006-12-27 EP disclosed
EP-1331218-A1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof MICHIGAN STATE UNIVERSITY (US) 2003-07-30 EP disclosed
EP-1331218-A1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof MICHIGAN STATE UNIVERSITY (US) 2003-07-30 EP disclosed
EP-1331218-A1 Process for the preparation of protected 3-amino-1,2-dihydroxy-propane acetal and derivatives thereof MICHIGAN STATE UNIVERSITY (US) 2003-07-30 EP disclosed
EP-1084099-B1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF UNIV MICHIGAN STATE (US) 2003-03-26 EP disclosed
EP-1084099-B1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF UNIV MICHIGAN STATE (US) 2003-03-26 EP disclosed
EP-1084099-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 2001-03-21 EP disclosed
EP-1084099-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 2001-03-21 EP disclosed
US-6040464-A Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-03-21 US disclosed
US-6040464-A Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-03-21 US disclosed
US-6040464-A Process for the preparation of protected 3-amino-1,2-dihydroxypropane acetal and derivatives thereof BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY (US) 2000-03-21 US disclosed
WO-1999062861-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 1999-12-09 WO disclosed
WO-1999062861-A1 PROCESS FOR THE PREPARATION OF PROTECTED 3-AMINO-1,2-DIHYDROXYPROPANE ACETAL AND DERIVATIVES THEREOF MICHIGAN STATE UNIVERSITY (US) 1999-12-09 WO disclosed