Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL10380801 | 0.93 | LMNA (0.57) | LMNATDP1TSHRTHRBHSD17B10 | |
| Propylene Glycol SCHEMBL1532415 | 0.91 | LMNA (0.55) | LMNATDP1TSHRTHRBHSD17B10 | |
| Propylene Glycol SCHEMBL872897 | 0.89 | LMNA (0.52) | LMNATDP1TSHRTHRB | |
| Propylene Glycol SCHEMBL9621813 | 0.87 | LMNA (0.50) | LMNATDP1TSHRALDH1A1 | |
| Propylene Glycol SCHEMBL16666994 | 0.87 | LMNA (0.50) | LMNATDP1TSHRHSD17B10ALDH1A1 | |
| Propylene Glycol SCHEMBL1245845 | 0.87 | LMNA (0.50) | LMNATDP1TSHRHSD17B10ALDH1A1 | |
| Glycerin SCHEMBL252728 | 0.86 | LMNA (0.63) | LMNATDP1TSHRTHRBALDH1A1 | |
| Isopropyl Alcohol SCHEMBL5499438 | 0.85 | LMNA (0.80) | LMNATDP1TSHRTHRBHSD17B10 | |
| Alcohol SCHEMBL1490179 | 0.85 | LMNA (0.80) | LMNATDP1TSHRTHRBALDH1A1 | |
| Hydroxyamine SCHEMBL7122122 | 0.85 | LMNA (0.80) | LMNATDP1TSHRTHRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359846-A | Resin intermediate and method for producing resin intermediate | 解合元(上海)资源再生科技有限公司 | 2024-07-19 | — | — | CN | claimed |
| CN-118165786-A | Development method of fragrant watermelon essence | 四川味欣生物科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117986554-A | Toughening additive and modified epoxy resin | 解合元(上海)资源再生科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| US-20240050337-A1 | A MIXTURE COMPRISING 1,2-ALKANEDIOLS | SYMRISE AG (DE) | 2024-02-15 | — | — | US | claimed |
| CN-116239619-A | Boron-containing micromolecular aldehyde hydrate and preparation method and application thereof | 高银华 | 2023-06-09 | — | — | CN | claimed |
| WO-2023072703-A1 | FILMS AND CAPSULES | UNILEVER IP HOLDINGS B.V. (NL) | 2023-05-04 | — | — | WO | claimed |
| EP-4096618-A1 | A MIXTURE COMPRISING 1,2-ALKANEDIOLS | Symrise AG (DE) | 2022-12-07 | — | — | EP | claimed |
| CN-217368309-U | Vanillin propylene glycol acetal is with negative pressure condensation device | 安徽锦戎香料有限公司 | 2022-09-06 | — | — | CN | claimed |
| WO-2022122143-A1 | A MIXTURE COMPRISING 1,2-ALKANEDIOLS | SYMRISE AG (DE) | 2022-06-16 | — | — | WO | claimed |
| US-20210139672-A1 | NOVEL COMPOSITIONS FOR BITTERANTS | UPL LTD (IN) | 2021-05-13 | — | — | US | claimed |
| WO-2005115325-A1 | MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-12-08 | — | — | WO | claimed |
| US-20050244561-A1 | Carvone acetals used as flavourings | SYMRISE GMBH & CO. KG (DE) | 2005-11-03 | — | — | US | claimed |
| US-6890567-B2 | Sensate composition imparting initial sensation upon contact | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-05-10 | — | — | US | claimed |
| US-20050027101-A1 | Attachment and elaboration strategies for inverse peptide synthesis | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2005-02-03 | — | — | US | claimed |
| US-20030198718-A1 | Process for improving the durability of, and/or stabilizing, microbially perishable products | SCHUR JORG PETER (DE) | 2003-10-23 | — | — | US | claimed |
| US-20030027982-A1 | Method for inverse solid phase synthesis of peptides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-02-06 | — | — | US | claimed |
| WO-2002094857-A1 | INVERSE SOLID PHASE SYNTHESIS OF PEPTIDES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2002-11-28 | — | — | WO | claimed |
| US-5626852-A | HYDROLYSIS OF ACETAL AND/OR KETAL | THE MENNEN COMPANY (US) | 1997-05-06 | — | — | US | claimed |
| WO-1994006441-A1 | COMPOSITION CONTAINING BODY ACTIVATED FRAGRANCE FOR CONTACTING THE SKIN AND METHOD OF USE | THE MENNEN COMPANY (US) | 1994-03-31 | — | — | WO | claimed |
| US-4851583-A | Method of generating acrolein | BETZ LABORATORIES, INC. (US) | 1989-07-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050337-A1 | A MIXTURE COMPRISING 1,2-ALKANEDIOLS | OR10J3, OR51E2, MAL2 | LMNA 3527/4885TDP1 3993/4885TSHR 4469/4885 |
| US-20030027982-A1 | Method for inverse solid phase synthesis of peptides | SSU72, SUB1, NPPA | LMNA 655/4885TDP1 3575/4885TSHR 198/4885 |
| US-20050027101-A1 | Attachment and elaboration strategies for inverse peptide synthesis | SCTR, NPPA, PTMS | LMNA 2267/4885TDP1 4185/4885TSHR 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.