Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670726 | 0.80 | CA1 (0.38) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL28846838 | 0.79 | CYP1A2 (0.34) | CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL28574831 | 0.77 | OPRM1 (0.41) | CYP1A2DPP7 | |
| SCHEMBL18434625 | 0.75 | EPHX1 (0.32) | — | |
| SCHEMBL7689323 | 0.75 | HIF1A (0.33) | — | |
| SCHEMBL349164 | 0.75 | ENPEP (0.46) | CYP1A2GSR | |
| SCHEMBL23092019 | 0.74 | — | — | |
| SCHEMBL6048824 | 0.74 | — | — | |
| SCHEMBL3958831 | 0.74 | — | — | |
| Sulfuric Acid SCHEMBL12803038 | 0.71 | TP53 (0.55) | DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615946-A2 | PROTEOLYTIC AND COVALENT ANTIBODIES | The University of Texas (US) | 2006-01-18 | — | — | EP | disclosed |
| EP-1610808-A2 | COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING | University of Texas Medical School (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087735-A2 | PROTEOLYTIC AND COVALENT ANTIBODIES | THE UNIVERSITY OF TEXAS (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004087059-A2 | COVALENT ATTACHMENT OF LIGANDS TO NUCLEOPHILIC PROTEINS GUIDED BY NON-COVALENT BINDING | THE UNIVERSITY OF TEXAS (US) | 2004-10-14 | — | — | WO | disclosed |