Methacrylic Acid

Methacrylic Acid

SCHEMBL6049026

C=C(C)C(=O)O.C=CC(=C)Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 4/20 0.40
TP53 P04637 1/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FGFR4 P22455 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroprene SCHEMBL150672 0.88
Methacrylic Acid SCHEMBL8749687 0.86 LMNA (0.53) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL27577962 0.83 ALDH1A1 (0.38) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL5964487 0.82 LMNA (0.62) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL9066064 0.82 LMNA (0.62) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL23071293 0.82 LMNA (0.62) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL10804851 0.82 ALDH1A1 (0.42) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL161378 0.82 ALDH1A1 (0.62) ALDH1A1TSHRTP53LMNATDP1
Methacrylic Acid SCHEMBL238111 0.82
Methacrylic Acid SCHEMBL9681348 0.82 LMNA (0.62) ALDH1A1TSHRTP53LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100415787-C Method for producing polychloroprene latex and composition DENKI KAGAKU KOGYO KK (JP) 2008-09-03 CN disclosed
JP-2006349741-A DEVELOPING ROLLER BRIDGESTONE CORP 2006-12-28 JP disclosed