Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130428 | 0.86 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL29812995 | 0.86 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL2393670 | 0.81 | IDO1 (0.48) | RXRARXRGIDO1DAOTACR1 | |
| SCHEMBL17319636 | 0.80 | RXRA (0.47) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL24108532 | 0.79 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL2390020 | 0.79 | RXRA (0.49) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL172834 | 0.79 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL129227 | 0.79 | RXRA (0.49) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL169517 | 0.79 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 | |
| SCHEMBL172532 | 0.79 | RXRA (0.46) | RXRARXRGMRGPRX4KIF11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008355-A | Azaindole derivatives as protein kinase inhibitors | ORIBASE PHARMA | 2015-10-28 | — | — | CN | disclosed |
| CN-103172562-B | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | TANABE SEIYAKU CO | 2015-04-22 | — | — | CN | disclosed |
| CN-101374817-B | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | MITSUBISHI TANABE PHARMA CORP | 2014-07-30 | — | — | CN | disclosed |
| CN-103172562-A | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | TANABE SEIYAKU CO | 2013-06-26 | — | — | CN | disclosed |
| CN-101466679-A | Process for preparing tetrahydroquinoline derivatives | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-06-24 | — | — | CN | disclosed |
| CN-101437804-A | Dibenzyl amine compounds and derivatives | PFIZER PROD INC (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-101374817-A | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-02-25 | — | — | CN | disclosed |
| CN-1289467-C | Dibenzylamine compound and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2006-12-13 | — | — | CN | disclosed |
| JP-2006045095-A | 3-FORMYL-5-TRIFLUOROMETHYLBENZONITRILE DERIVATIVE AND METHOD FOR PRODUCING THE SAME | CENTRAL GLASS CO LTD | 2006-02-16 | — | — | JP | disclosed |
| CN-1617850-A | Dibenzylamine compound and medicinal use thereof | JAPAN TOBACCO INC (JP) | 2005-05-18 | — | — | CN | disclosed |