Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6049202 | 0.99 | SLC6A4 (0.52) | SLC6A4MEN1KMT2ACA1CA2 | |
| SCHEMBL6049188 | 0.88 | SLC6A4 (0.54) | SLC6A4MEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6049215 | 0.77 | SLC6A4 (0.51) | SLC6A4CA1CA2CA9CA7 | |
| Hydrochloric Acid SCHEMBL6049196 | 0.77 | MEN1 (0.48) | SLC6A4MEN1KMT2ASLC6A3SMN1; SMN2 | |
| SCHEMBL6049182 | 0.76 | SLC6A4 (0.49) | SLC6A4CA1CA2CA9CA7 | |
| Uk-390957 SCHEMBL931652 | 0.69 | SLC6A4 (1.00) | SLC6A4SLC6A3SOS1 | |
| SCHEMBL15080486 | 0.68 | SLC6A4 (0.72) | SLC6A4SLC6A3 | |
| SCHEMBL6049203 | 0.66 | KIF11 (0.48) | SLC6A4MEN1KMT2ASLC6A3 | |
| Hydrochloric Acid SCHEMBL6049178 | 0.65 | SLC6A4 (0.53) | SLC6A4MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6049201 | 0.65 | TACR1 (0.40) | SLC6A4MEN1KMT2ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184372-B1 | Phenoxyphenylheterocycle derivatives as selective serotonin reuptake inhibitors (SSRIs) | PFIZER LTD (GB) | 2006-04-26 | — | — | EP | claimed |