Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435359 | 0.87 | TDP1 (0.47) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL962297 | 0.86 | TDP1 (0.64) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL7216069 | 0.84 | TDP1 (0.60) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL26454774 | 0.81 | TDP1 (0.66) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL26455392 | 0.81 | TDP1 (0.66) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL14379637 | 0.81 | TDP1 (0.45) | TDP1LMNATSHRMAPK1L3MBTL1 | |
| SCHEMBL14379706 | 0.81 | TDP1 (0.39) | TDP1LMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7210111 | 0.81 | LMNA (0.56) | TDP1LMNATSHRMAPK1SLC6A3 | |
| SCHEMBL14379663 | 0.80 | TDP1 (0.44) | TDP1LMNATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL6273987 | 0.80 | TDP1 (0.64) | TDP1LMNATSHRMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006225358-A | SILOXANE ESTER COMPOUND, OIL COMPONENT FOR SKIN CARE PREPARATION OR HAIR COSMETIC, AND SKIN CARE PREPARATION OR HAIR COSMETIC PREPARED BY COMPOUNDING THE OIL COMPONENT | SHISEIDO CO LTD | 2006-08-31 | — | — | JP | disclosed |