Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.59 |
| ▸ | PPARG | P37231 | 12/20 | 0.59 |
| ▸ | PPARD | Q03181 | 8/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964391 | 1.00 | PPARA (0.59) | PPARAPPARGPPARDTRPM8CNR2 | |
| SCHEMBL3963119 | 1.00 | PPARA (0.59) | PPARAPPARGPPARDTRPM8CNR2 | |
| SCHEMBL3962797 | 0.96 | PPARA (0.61) | PPARAPPARGPPARDTRPM8 | |
| SCHEMBL3960482 | 0.94 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3964912 | 0.93 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL3960794 | 0.92 | TRPM8 (0.52) | PPARAPPARGPPARDTRPM8CNR2 | |
| SCHEMBL3963033 | 0.92 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3960095 | 0.92 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL3967803 | 0.92 | PPARA (0.56) | PPARAPPARGPPARDCNR2 | |
| SCHEMBL3960947 | 0.92 | PPARA (0.66) | PPARAPPARGPPARDTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902367-B2 | Cyclic amino benzoic acid derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-7514471-B2 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor α (PPAR) | ASTRAZENECA AB (SE) | 2009-04-07 | — | — | US | disclosed |
| US-7488844-B2 | Therapeutic agents | ASTRAZENECA AB (SE) | 2009-02-10 | — | — | US | disclosed |
| US-20090036489-A1 | Novel Cyclic Aminophenylalkanoic Acid Derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20080114064-A1 | Tri(Hydroxymethyl)Methylamine Salt or an Ethanol Amine Salt of (2S)-2-Ethoxy-3-(4-PHENYL) Propanoic Acid | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| US-20070249580-A1 | Novel Cyclic Amino Benzoic Acid Derivative | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1458673-B1 | SUBSTITUTED PHENYLPROPIONIC ACID DERIVATIVES AS AGONISTS TO HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA (PPAR) | ASTRAZENECA AB (SE) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036489-A1 | Novel Cyclic Aminophenylalkanoic Acid Derivative | PPARA, PPARD, PPARG | PPARA 1/4885PPARG 3/4885PPARD 2/4885 |
| US-20080114064-A1 | Tri(Hydroxymethyl)Methylamine Salt or an Ethanol Amine Salt of (2S)-2-Ethoxy-3-(4-PHENYL) Propanoic Acid | PNMT, TET3, TET1 | PPARA 1083/4885PPARG 2420/4885PPARD 1805/4885 |
| US-20070249580-A1 | Novel Cyclic Amino Benzoic Acid Derivative | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.