SCHEMBL6049815

SCHEMBL6049815

[CH2]COC(COc1ccccc1)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
SCN4A P35499 2/20 0.43
MAOA P21397 1/20 0.41
PTGS1 P23219 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
KCNA3 P22001 1/20 0.39
MTNR1A P48039 3/20 0.37
MTNR1B P49286 3/20 0.37
CYP2D6 P10635 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
KDM4E B2RXH2 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29193930 0.77 SCN4A (0.50) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL2112807 0.77 LMNA (0.47) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL11509827 0.74 LTA4H (0.34) LMNAMAOAPTGS1PPARGPPARA
SCHEMBL16167284 0.73 LTA4H (0.39) LMNASCN4APPARGPPARAKCNA3
SCHEMBL293722 0.73 LMNA (0.47) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL2048947 0.73 PPARG (0.43) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL294015 0.72 LMNA (0.50) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL13960149 0.71 LMNA (0.54) LMNASCN4AMAOAPTGS1PPARG
SCHEMBL1193076 0.71 LMNA (0.53) LMNASCN4AMAOAPTGS1KCNA3
SCHEMBL11279932 0.71 KDM4E (0.41) LMNAMAOAPTGS1MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577438-B2 Polyfunctional polymer and method for producing same MITSUI CHEMICALS TOHCELLO, INC. (JP) 2020-03-03 US disclosed
US-20180244811-A1 POLYFUNCTIONAL POLYMER AND METHOD FOR PRODUCING SAME MITSUI CHEMICALS TOHCELLO, INC. (JP) 2018-08-30 US disclosed
EP-3351568-A1 POLYFUNCTIONAL POLYMER AND METHOD FOR PRODUCING SAME Mitsui Chemicals Tohcello, Inc. (JP) 2018-07-25 EP disclosed
US-9068024-B2 2,2-dimethoxy-1,2-DI[4-(meth)acryloyloxy]phenylethane-1-one, method for producing the same, radical polymerization initiator and photocurable composition TOYO GOSEI CO., LTD. (JP) 2015-06-30 US disclosed
US-20130324633-A1 2,2-DIMETHOXY-1,2-DI[4-(METH)ACRYLOYLOXY]PHENYLETHANE-1-ONE, METHOD FOR PRODUCING THE SAME, RADICAL POLYMERIZATION INITIATOR AND PHOTOCURABLE COMPOSITION TOYO GOSEI CO., LTD (JP) 2013-12-05 US disclosed
EP-1354918-B1 Curable resin composition, method for manufacture of laminate using the composition, transfer material, method for manufacture thereof and transferred product KURARAY CO (JP) 2006-03-08 EP disclosed
US-20030236318-A1 Curable resin composition, method for manufacture of laminate using the composition, transfer material, method for manufacture thereof and transferred product KURARAY CO., LTD. (JP) 2003-12-25 US disclosed
EP-1354918-A1 Curable resin composition, method for manufacture of laminate using the composition, transfer material, method for manufacture thereof and transferred product KURARAY CO., LTD. (JP) 2003-10-22 EP disclosed