SCHEMBL6049844

SCHEMBL6049844

OC1CCC(N=C=S)CC1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
APLNR P35414 4/20 0.74
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14282690 0.89 APLNR (0.58) APLNR
SCHEMBL289935 0.86
SCHEMBL3903198 0.86 APLNR (1.00) APLNREPHX1HIF1A
SCHEMBL710256 0.75
SCHEMBL6081194 0.75
SCHEMBL14621170 0.74 ALDH1A1 (0.56) APLNRTSHREPHX1HIF1A
SCHEMBL331120 0.74 APLNR (0.74) APLNREPHX1HIF1A
SCHEMBL13459214 0.72 APLNR (0.72) APLNREPHX1HIF1A
SCHEMBL16307180 0.72 APLNR (0.72) APLNREPHX1HIF1A
SCHEMBL15492395 0.72 APLNR (0.72) APLNREPHX1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1180933-B1 COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL ILLOVO SUGAR LTD (ZA) 2006-11-15 EP disclosed
EP-1180933-A4 COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL ILLOVO SUGAR LTD (ZA) 2006-01-04 EP disclosed
CN-1221172-C Compsns. and process for nematode control ILLOVO SUGAR LTD (ZA) 2005-10-05 CN disclosed
US-6720352-B1 HETEROCYCLIC ALDEHYDES; ISOTHIOCYANATES; FURFURAL; METHYL ISOTHIOCYANTATE; ALLYL ISOTHIOCYANATE; CROPS ILLOVO SUGAR LIMITED (ZA) 2004-04-13 US disclosed
CN-1356871-A Compositions and methods for controlling nematodes ILLOVO SUGAR LTD (ZA) 2002-07-03 CN disclosed
EP-1180933-A1 COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL Illovo Sugar Limited (ZA) 2002-02-27 EP disclosed
WO-2000067577-A1 COMPOSITIONS AND PROCESS FOR NEMATODE CONTROL ILLOVO SUGAR LIMITED (ZA) 2000-11-16 WO disclosed