Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227628 | 0.90 | CA1 (0.59) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL11222499 | 0.90 | CA1 (0.59) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL6533202 | 0.83 | CA1 (0.56) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL13557323 | 0.80 | MEN1 (0.47) | HTTLMNACYP1A2GAAMEN1 | |
| SCHEMBL10765175 | 0.80 | CA1 (0.56) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL10537396 | 0.80 | CA1 (0.70) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL4444431 | 0.80 | CA1 (0.70) | TDP1MAPTCA1CA2CA12 | |
| SCHEMBL11106829 | 0.79 | ALOX15 (0.54) | CA1CA2GAAHPGDKMT2A | |
| SCHEMBL13924144 | 0.79 | SMN1; SMN2 (0.50) | TDP1HTTLMNARAB9AGAA | |
| SCHEMBL5209871 | 0.79 | ESR1 (0.53) | TDP1MAPTCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405841-B1 | PROCESS FOR PREPARATION OF 2-OXOCARBOXYLIC ACID ESTERS | KURARAY CO (JP) | 2006-08-16 | — | — | EP | disclosed |
| US-6897335-B2 | Process for preparation of 2-oxocarboxylic acid esters | KURARAY CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |
| US-20040162441-A1 | Process for preparation of 2-oxocarboxylic acid esters | KURARAY CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1405841-A1 | PROCESS FOR PREPARATION OF 2-OXOCARBOXYLIC ACID ESTERS | KURARAY CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162441-A1 | Process for preparation of 2-oxocarboxylic acid esters | HAO2, HACL2, HAO1 | TDP1 4399/4885MAPT 4867/4885CA1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.