SCHEMBL60506

SCHEMBL60506

O=C(O)C(Cc1c[nH]cn1)NCF

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 7/20 0.37
CPB1 P15086 1/20 0.37
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301850 1.00 CPB2 (0.37) CPB2CPB1ALDH1A1CYP1A2CYP3A4
SCHEMBL933574 1.00 CPB2 (0.37) CPB2CPB1ALDH1A1CYP1A2CYP3A4
Fluoride SCHEMBL27998040 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10980804 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10981835 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10976751 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL9186803 0.97 CPB2 (0.36) CPB2CPB1
SCHEMBL15665199 0.93 CPB2 (0.36) CPB2CPB1
SCHEMBL5984088 0.91 TNF (0.41) CPB2CPB1ALDH1A1
Tetrahydrofuran SCHEMBL10977306 0.90 CPB2 (0.32) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1703 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197916-A1 METHODS AND COMPOSITIONS FOR SUPPRESSION OF BIOGENIC AMINES PRODUCED BY THE GUT MICROBIOME CEDARS-SINAI MEDICAL CENTER (US) 2025-06-19 US claimed
EP-3891176-B1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE HOLST BIRGITTE (DK) 2024-06-05 EP claimed
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 EP claimed
EP-3077008-B1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (CN) 2023-10-04 EP claimed
US-20230043198-A1 MICROBIOTA METABOLITES THAT SHAPE HOST PHYSIOLOGY YALE UNIVERSITY (US) 2023-02-09 US claimed
CN-112043835-B Bioreversible introducing group for nitrogen and hydroxyl-containing drugs 韩捷 2022-10-21 CN claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 EP claimed
US-20220056077-A1 DUAL AGONIST GLP-1 AND NEUROTENSIN FUSION PEPTIDE RATNER, Cecilia (DK) 2022-02-24 US claimed
CN-107205948-B Tablets comprising a GLP-1 agonist and an enteric coating 诺和诺德股份有限公司 2021-12-14 CN claimed
WO-1996026712-A2 USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH HANDELMAN, JOSEPH, H. (US) 1996-09-06 WO claimed
EP-0180597-B1 COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS RICHARDSON-VICKS, INC. (US) 1992-03-04 EP claimed
US-4876246-A Benzo[a]phenothiazines and hydro-derivatives for inhibiting leukotriene biosynthesis MERCK FROSST CANADA, INC. (CA) 1989-10-24 US claimed
EP-0109036-B1 ANTI-INFLAMMATORY/ANALGESIC COMBINATION OF ALPHA-FLUOROMETHYLHISTIDINE AND A SELECTED NON-STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID) MERCK & CO. INC. (US) 1987-09-02 EP claimed
EP-0073971-B1 THIADIAZOLE OXIDES AS GASTRIC ANTISECRETORY AGENTS MERCK & CO. INC. (US) 1986-05-21 EP claimed
US-4522823-A Orexigenic use of α-fluoromethyl-histidine MERCK & CO., INC. (US) 1985-06-11 US claimed
EP-0109036-A1 Anti-inflammatory/analgesic combination of alpha-fluoromethylhistidine and a selected non-steroidal anti-inflammatory drug (NSAID) MERCK & CO. INC. (US) 1984-05-23 EP claimed
US-4447443-A SYNERGISTIC MIXTURE MERCK & CO., INC. (US) 1984-05-08 US claimed
US-4411899-A Substituted derivatives of amino alkane diols as gastric secretion inhibitors MERCK & CO., INC. (US) 1983-10-25 US claimed
EP-0082376-A2 Substituted derivatives of amino alkane diols as gastric secretion inhibitors MERCK & CO. INC. (US) 1983-06-29 EP claimed