SCHEMBL933574

SCHEMBL933574

O=C(O)[C@H](Cc1c[nH]cn1)NCF

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 7/20 0.37
CPB1 P15086 1/20 0.37
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301850 1.00 CPB2 (0.37) CPB2CPB1ALDH1A1CYP1A2CYP3A4
SCHEMBL60506 1.00 CPB2 (0.37) CPB2CPB1ALDH1A1CYP1A2CYP3A4
Fluoride SCHEMBL27998040 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10980804 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10981835 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL10976751 0.98 CPB2 (0.36) CPB2CPB1
Hydrochloric Acid SCHEMBL9186803 0.97 CPB2 (0.36) CPB2CPB1
SCHEMBL15665199 0.93 CPB2 (0.36) CPB2CPB1
SCHEMBL5984088 0.91 TNF (0.41) CPB2CPB1ALDH1A1
Tetrahydrofuran SCHEMBL10977306 0.90 CPB2 (0.32) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778530-A Method for adding preset joint to 5' end of single-stranded DNA 清华大学 2024-03-29 CN claimed
EP-3077008-B1 BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS HAN JIE (CN) 2023-10-04 EP claimed
EP-2932981-B1 Albumin-binding derivatives of GLP-1 NOVO NORDISK AS (DK) 2021-06-16 EP claimed
EP-3225631-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2019-01-09 EP claimed
EP-2190873-B1 TRUNCATED GLP-1 DERIVATIVES AND THEIR THERAPEUTICAL USE NOVO NORDISK AS (DK) 2015-07-22 EP claimed
EP-2571897-B1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE BETTA PHARMACEUTICALS CO LTD (CN) 2014-11-05 EP claimed
EP-2007804-B1 GLP-1 COMPOUNDS AMGEN INC (US) 2014-06-18 EP claimed
EP-2729481-A1 ENGINEERED POLYPEPTIDES HAVING ENHANCED DURATION OF ACTION WITH REDUCED IMMUNOGENICITY Amylin Pharmaceuticals, LLC (US) 2014-05-14 EP claimed
WO-2013009545-A1 ENGINEERED POLYPEPTIDES HAVING ENHANCED DURATION OF ACTION WITH REDUCED IMMUNOGENICITY AMYLIN PHARMACEUTICALS, INC. (US) 2013-01-17 WO claimed
EP-1605897-B1 POLYETHELENE GLYCOL LINK GLP-1 COMPOUNDS LILLY CO ELI (US) 2012-07-25 EP claimed
EP-0812185-B1 USE OF ANGIOGENESIS SUPPRESSORS FOR INHIBITING HAIR GROWTH GILLETTE CO (US) 2002-07-03 EP claimed
WO-2002046227-A2 GLP-1 FUSION PROTEINS ELI LILLY AND COMPANY (US) 2002-06-13 WO claimed
WO-1998043658-A1 GLUCAGON-LIKE PEPTIDE-1 ANALOGS ELI LILLY AND COMPANY (US) 1998-10-08 WO claimed
EP-0481675-B1 Preparation of medicaments for treating asthma using (S)-alpha-fluoromethyl histidine and esters thereof KOLLONITSCH JANOS DR (US) 1995-09-27 EP claimed
EP-0481675-A2 Preparation of medicaments for treating asthma using (S)-alpha-fluoromethyl histidine and esters thereof Kollonitsch, Janos, Dr. (US) 1992-04-22 EP claimed
EP-0180597-B1 COUGH/COLD MIXTURES COMPRISING NON-STEROIDAL ANTI-INFLAMMATORY DRUGS RICHARDSON-VICKS, INC. (US) 1992-03-04 EP claimed
US-5030645-A Method of treating asthma using (S)-α-fluoromethyl-histidine and esters thereof MERCK & CO., INC. (US) 1991-07-09 US claimed
EP-0109036-B1 ANTI-INFLAMMATORY/ANALGESIC COMBINATION OF ALPHA-FLUOROMETHYLHISTIDINE AND A SELECTED NON-STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID) MERCK & CO. INC. (US) 1987-09-02 EP claimed
EP-0046290-B1 SYNERGISTIC COMBINATION OF (R,S)ALPHA-FLUOROMETHYLHISTIDINE AND CIMETIDINE AS AN ANTI-ULCER AGENT MERCK & CO. INC. (US) 1985-01-02 EP claimed
EP-0046290-A1 Synergistic combination of (R,S)alpha-fluoromethylhistidine and cimetidine as an anti-ulcer agent MERCK & CO. INC. (US) 1982-02-24 EP claimed