SCHEMBL6050852

SCHEMBL6050852

[SeH][Se]c1ccnc(-c2cc3cccc4ccc5c6ccccc6[c]c2c5c43)n1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.35
CYP1A2 P05177 1/20 0.35
FYN P06241 1/20 0.35
MAOA P21397 1/20 0.35
ACHE P22303 1/20 0.35
AHR P35869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6742211 0.74 CYP1A2 (0.50) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL7774162 0.69 CYP1A2 (0.49) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL6050883 0.68 CYP1A2 (0.39) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL18546810 0.66 HSD17B10 (0.57) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17083456 0.64 CYP1A2 (0.45) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL55779 0.63 HSD17B10 (0.50) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17083465 0.62 CYP1A2 (0.42) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL27865920 0.62 CYP1A2 (0.48) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17083457 0.61 CYP1A2 (0.41) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17691982 0.59 ALDH1A1 (0.44) ERBB2CYP1A2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1636232-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA Bioscience nv (BE) 2006-03-22 EP disclosed
WO-2004104005-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2004-12-02 WO disclosed