Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77080 | 0.94 | PLA2G4B (0.33) | TP53SMN1; SMN2MAPK1PLA2G4BNPC1 | |
| SCHEMBL20604121 | 0.94 | PLA2G4B (0.33) | TP53SMN1; SMN2MAPK1PLA2G4BNPC1 | |
| SCHEMBL28354317 | 0.90 | CDK4 (0.32) | TP53SMN1; SMN2MAPK1PLA2G4BNPC1 | |
| SCHEMBL22017460 | 0.90 | PLA2G4B (0.35) | TP53SMN1; SMN2MAPK1PLA2G4BLMNA | |
| SCHEMBL12755375 | 0.88 | PLA2G4B (0.38) | MAPK1PLA2G4BNPC1POLBRAB9A | |
| SCHEMBL8910146 | 0.88 | PLA2G4B (0.33) | SMN1; SMN2MAPK1PLA2G4BNPC1RAB9A | |
| SCHEMBL16083397 | 0.88 | PLA2G4B (0.33) | SMN1; SMN2MAPK1PLA2G4BNPC1RAB9A | |
| SCHEMBL14431829 | 0.86 | ADRB2 (0.36) | SMN1; SMN2NPC1POLBRAB9ALMNA | |
| SCHEMBL6051254 | 0.86 | PLA2G4B (0.43) | TP53SMN1; SMN2MAPK1TLR8PLA2G4B | |
| SCHEMBL20024340 | 0.85 | LMNA (0.37) | TP53SMN1; SMN2MAPK1TLR8NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680463-A2 | STABILIZER COMPOSITIONS FOR HALOGEN CONTAINING POLYMERS | Ciba SC Holding AG (CH) | 2006-07-19 | — | — | EP | disclosed |
| EP-1539873-A2 | STABILLIZATION OF ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2005049715-A2 | STABILIZER COMPOSITIONS FOR HALOGEN CONTAINING POLYMERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-06-02 | — | — | WO | disclosed |
| WO-2004024810-A2 | STABILLIZATION OF ORGANIC MATERIALS | CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-25 | — | — | WO | disclosed |