SCHEMBL6052

SCHEMBL6052

O=C1C2C3C=CC(C3)C2C(=O)N1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
TDP1 Q9NUW8 1/20 1.00
SMN1; SMN2 Q16637 5/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
RAB9A P51151 2/20 0.53
HTT P42858 3/20 0.53
USP2 O75604 3/20 0.53
TSHR P16473 2/20 0.53
HSD17B10 Q99714 2/20 0.53
RECQL P46063 2/20 0.52
LMNA P02545 1/20 0.52
MAPK1 P28482 1/20 0.52
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.46
POLB P06746 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29900107 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL22922483 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL18049094 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL18386589 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL525258 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL30734372 1.00 ALDH1A1 (1.00) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL31289550 0.86 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2L3MBTL1KMT2A
Toluene SCHEMBL29171791 0.84 ALDH1A1 (0.70) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL28408842 0.80 ALDH1A1 (0.64) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL16592563 0.78 ALDH1A1 (0.64) ALDH1A1TDP1SMN1; SMN2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3543 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662222-A1 PROCESS FOR THE PREPARATION OF TETRAPEPTIDE FRAGMENT OF LIRAGLUTIDE Fresenius Kabi Oncology Ltd (IN) 2025-12-17 EP claimed
CN-120192263-A Preparation of 2- (endo-5-norbornene-2, 3-dicarboximide) -1, 3-tetramethylurea hexafluorophosphate 张家港市国泰华荣化工新材料有限公司 2025-06-24 CN claimed
US-20250197534-A1 ENZYME-MEDIATED FREE RADICAL INITIATING SYSTEMS FOR THE PRODUCTION OF HYDROGELS AND CONTROLLED RADICAL POLYMERIZATION PROCESSES DUKE UNIVERSITY 2025-06-19 US claimed
CN-119019649-B Cycloolefin polymer and preparation method thereof 中石油(上海)新材料研究院有限公司 2025-06-03 CN claimed
CN-120058841-A Synthesis method of snake venom tetrapeptide 上海鲲诺生物科技有限公司 2025-05-30 CN claimed
CN-119708196-A Tenipout peptide synthesis method 深圳翰宇药业股份有限公司 2025-03-28 CN claimed
CN-119708125-A Solid phase synthesis method of antibacterial bakuchiol derivative 山东创新药物研发有限公司 2025-03-28 CN claimed
US-12247090-B2 Enzyme-mediated free radical initiating systems for the production of hydrogels and controlled radical polymerization processes DUKE UNIVERSITY (US) 2025-03-11 US claimed
CN-118745608-B Flame-retardant antistatic composite modified polyester fiber and preparation method thereof 常州市锦纶厂有限公司 2025-02-18 CN claimed
US-20250034290-A1 Functional Cyclic Olefin Polymer, Process for Obtaining the Same and Compositions Containing the Same EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-01-30 US claimed
EP-0219070-B1 A PROCESS FOR PREPARING N-GLYCOLYLNEURAMINIC ACID DERIVATIVES MECT CORPORATION (JP) 1989-06-21 EP claimed
US-4774326-A ANTITUMOR ANTIGENS, AMIDATION WITH GLYCOLIC ACID MECT CORPORATION (JP) 1988-09-27 US claimed
CN-87108160-A Preparation and application have the method for the sialic acid derivative of active carbonyl group 1988-09-14 CN claimed
EP-0273388-A2 Sialic acid derivatives having active carbonyl group MECT CORPORATION (JP) 1988-07-06 EP claimed
EP-0134041-B1 N-CHLOROCARBONYLOXY-5-NORBORNENE-2,3-DICARBOXIMIDE, PROCESS FOR ITS PREPARATION AND ITS USE Akademie der Wissenschaften der DDR (DE) 1988-04-06 EP claimed
EP-0107119-B1 BLOOD-TREATING MATERIAL TORAY INDUSTRIES, INC. (JP) 1987-02-04 EP claimed
EP-0160925-A2 N-substituted neuraminic acid derivatives and process for preparation thereof MECT Corporation (JP) 1985-11-13 EP claimed
EP-0107119-A1 Blood-treating material TORAY INDUSTRIES, INC. (JP) 1984-05-02 EP claimed
US-4347354-A Preparation of 1-N-[ω-amino-α-hydroxyalkanoyl]aminoglycoside polysilylated antibiotics and products obtained therefrom BRISTOL-MYERS COMPANY (US) 1982-08-31 US claimed
US-4174312-A ACYLATION, HYDROLYSIS, SALT FORMATION, CATALYTIC HYDROGENATION ABBOTT LABORATORIES (US) 1979-11-13 US claimed