Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | GAA | P10253 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052095 | 1.00 | ALDH1A1 (0.73) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL18186377 | 0.83 | HTT (0.63) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL10126809 | 0.82 | HTT (0.69) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL1046567 | 0.81 | HTT (0.67) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL994308 | 0.81 | HTT (0.80) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL1046568 | 0.81 | HTT (0.67) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL18186283 | 0.80 | HTT (0.66) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL993768 | 0.79 | HTT (0.64) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL993767 | 0.79 | HTT (0.64) | ALDH1A1GAASMN1; SMN2HTTLMNA | |
| SCHEMBL30366718 | 0.79 | HTT (0.64) | ALDH1A1GAASMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |