Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594432 | 0.89 | MAPT (0.54) | GPR119NR1H2GAAMAPTHSD17B10 | |
| SCHEMBL29665264 | 0.89 | MAPT (0.54) | GPR119NR1H2GAAMAPTHSD17B10 | |
| SCHEMBL24351663 | 0.85 | HRH3 (0.51) | GPR119NR1H2GAAHRH3OPRM1 | |
| SCHEMBL6052351 | 0.85 | MAPT (0.50) | GPR119NR1H2GAAMAPTHSD17B10 | |
| SCHEMBL25194818 | 0.84 | KDM4E (0.46) | GPR119NR1H2MAPTHRH3 | |
| SCHEMBL10126921 | 0.82 | HRH3 (0.47) | GPR119NR1H2GAAMAPTHRH3 | |
| SCHEMBL13313520 | 0.81 | GPR119 (0.59) | GPR119MAPTHRH3 | |
| SCHEMBL31333261 | 0.81 | HRH3 (0.51) | GPR119NR1H2GAAMAPTHRH3 | |
| SCHEMBL6052489 | 0.80 | MAPT (0.50) | IRAK4GAAMAPTHSD17B10 | |
| SCHEMBL20884909 | 0.79 | GPR119 (0.52) | GPR119NR1H2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |