SCHEMBL6052206

SCHEMBL6052206

O=C(C(F)(F)Br)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891907 0.82 THRB (0.48) THRB
SCHEMBL20377905 0.81 THRB (0.39) THRBLMNA
SCHEMBL4575999 0.77 THRB (0.43) THRB
SCHEMBL926832 0.77 THRB (0.43) THRB
SCHEMBL2275318 0.77 THRB (0.43) THRB
SCHEMBL942872 0.74 THRB (0.42) THRB
Silver SCHEMBL30466744 0.74 THRB (0.42) THRB
SCHEMBL20377904 0.74 THRB (0.33) THRB
SCHEMBL29133533 0.73 THRB (0.60) THRBLMNA
SCHEMBL15758530 0.72 THRB (0.40) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122704-B2 Fluoroketone compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 2006-10-17 US disclosed
US-20050033095-A1 Fluoroketone compounds E. I. DU PONT DE NEMOURS AND COMPANY 2005-02-10 US disclosed