SCHEMBL6052249

SCHEMBL6052249

Cc1cc(C(=O)Nc2ccc(OCC(C)(C)C)c(C#N)c2)nn1-c1ccc(F)cc1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 4/20 0.49
XDH P47989 2/20 0.44
RIPK1 Q13546 1/20 0.41
MAPT P10636 1/20 0.41
PTGER1 P34995 1/20 0.41
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6052208 0.86 KMT2A (0.46) XDHMAPT
SCHEMBL6052423 0.86 AR (0.45) XDHMAPTAR
Water SCHEMBL6052673 0.83 MET (0.51) XDH
SCHEMBL6052355 0.83 MET (0.51) XDH
SCHEMBL6052323 0.83 XDH (0.47) XDHMAPTAR
SCHEMBL6052642 0.82 XDH (0.48) XDHAR
SCHEMBL6052657 0.80 XDH (0.47) XDHMAPT
SCHEMBL7060223 0.80 AR (0.49) XDHAR
SCHEMBL7061255 0.79 XDH (0.47) XDHAR
SCHEMBL6052437 0.79 XDH (0.65) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7015218-B1 Amide compounds and medicinal use thereof MITSUBISHI PHARMA CORPORATION (JP) 2006-03-21 US disclosed
EP-1176140-B1 AMIDE COMPOUNDS AND MEDICINAL USE THEREOF MITSUBISHI PHARMA CORP (JP) 2004-12-29 EP disclosed
EP-1176140-A1 AMIDE COMPOUNDS AND MEDICINAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2002-01-30 EP disclosed