Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052501 | 0.93 | NPY2R (0.49) | NPC1RAB9APKMNR1H4KDM4E | |
| SCHEMBL6052241 | 0.92 | MAPT (0.45) | NPC1RAB9APKMNR1H4KDM4E | |
| Water SCHEMBL6052346 | 0.92 | MAPT (0.44) | NPC1RAB9APKMNR1H4KDM4E | |
| SCHEMBL6052669 | 0.91 | MAPT (0.44) | NPC1RAB9APKMNR1H4KDM4E | |
| Water SCHEMBL6052396 | 0.91 | MAPT (0.44) | NPC1RAB9APKMNR1H4KDM4E | |
| SCHEMBL6052177 | 0.90 | MAPT (0.45) | NPC1RAB9ANR1H4KDM4EMAPT | |
| Water SCHEMBL6052275 | 0.89 | RAB9A (0.48) | NPC1RAB9APKMNR1H4KDM4E | |
| Dimethylformamide SCHEMBL6052453 | 0.88 | RAB9A (0.46) | NPC1RAB9APKMNR1H4KDM4E | |
| SCHEMBL6052652 | 0.86 | CYP2C9 (0.50) | NPC1RAB9APKMNR1H4KDM4E | |
| SCHEMBL6902923 | 0.86 | NR1H4 (0.43) | NPC1RAB9ANR1H4MAPTFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |