Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6052217 | 0.99 | NR1H4 (0.43) | NR1H4NPC1RAB9ACCR1FGFR1 | |
| SCHEMBL6052501 | 0.91 | NPY2R (0.49) | NR1H4NPC1RAB9AMAPTALDH1A1 | |
| Water SCHEMBL6052649 | 0.90 | NR1H4 (0.46) | NR1H4NPC1RAB9AFGFR1P2RY12 | |
| Dimethylformamide SCHEMBL6052453 | 0.87 | RAB9A (0.46) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| SCHEMBL6052292 | 0.86 | NPC1 (0.47) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| SCHEMBL6052241 | 0.84 | MAPT (0.45) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| Water SCHEMBL6052346 | 0.84 | MAPT (0.44) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| Water SCHEMBL6052396 | 0.83 | MAPT (0.44) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| SCHEMBL6052669 | 0.83 | MAPT (0.44) | NR1H4NPC1RAB9AFGFR1DDR2 | |
| SCHEMBL6052503 | 0.82 | SMN1; SMN2 (0.53) | NR1H4NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |