Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076270 | 0.85 | MAPT (0.59) | MAPK14MAPTPOLBSMN1; SMN2ALKBH1 | |
| SCHEMBL10366110 | 0.84 | ALKBH1 (0.45) | PTPN1MAPK14MAPTPOLBSMN1; SMN2 | |
| SCHEMBL27681344 | 0.82 | ALKBH1 (0.46) | PTPN1MAPK14MAPTPOLBSMN1; SMN2 | |
| SCHEMBL10364585 | 0.82 | PTPN1 (0.46) | PTPN1MAPK14MAPTKMT2AMEN1 | |
| SCHEMBL10373425 | 0.82 | NPC1 (0.50) | PTPN1MAPK14MAPTPOLB | |
| SCHEMBL1074233 | 0.81 | MAPK1 (0.58) | PTPN1MAPK14MAPTPOLBSMN1; SMN2 | |
| SCHEMBL2792560 | 0.81 | MAPK14 (0.72) | PTPN1MAPK14KMT2AMEN1KDM4E | |
| SCHEMBL10365375 | 0.80 | PTPN1 (0.57) | PTPN1MAPK14MAPTSMN1; SMN2ALKBH1 | |
| SCHEMBL10364975 | 0.79 | NPSR1 (0.51) | MAPT | |
| SCHEMBL6052569 | 0.79 | ALDH1A1 (0.57) | MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |