Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033491 | 0.85 | POLB (0.43) | POLBSSTR1SSTR4LMNAEPHX1 | |
| SCHEMBL5348003 | 0.83 | POLB (0.55) | POLBLMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8830804 | 0.82 | POLB (0.41) | POLBSSTR1SSTR4SMN1; SMN2MEN1 | |
| SCHEMBL14592561 | 0.77 | SSTR1 (0.41) | POLBSSTR1SSTR4LMNAHPGD | |
| SCHEMBL6052833 | 0.74 | ALDH1A1 (0.37) | POLBSSTR1SSTR4LMNAALDH1A1 | |
| SCHEMBL17483907 | 0.74 | TACR1 (0.50) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8830753 | 0.73 | TACR1 (0.41) | POLBHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL8830783 | 0.73 | TACR1 (0.46) | POLBEPHX1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL27936295 | 0.72 | MEN1 (0.38) | POLBLMNAEPHX1ALDH1A1MEN1 | |
| SCHEMBL15641282 | 0.72 | LMNA (0.35) | POLBSSTR1SSTR4LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429273-A | Synthesis method of metconazole intermediate | 江苏省农用激素工程技术研究中心有限公司 | 2021-09-24 | — | — | CN | disclosed |
| EP-2719695-B1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND | KUREHA CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-9241488-B2 | Azole derivative, method for producing azole derivative, and intermediate compound | KUREHA CORPORATION (JP) | 2016-01-26 | — | — | US | disclosed |
| US-20140113815-A1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND | KUREHA CORPORATION (JP) | 2014-04-24 | — | — | US | disclosed |
| EP-2719695-A1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND | Kureha Corporation (JP) | 2014-04-16 | — | — | EP | disclosed |
| EP-1308432-B1 | PROCESS FOR THE PREPARATION OF 5- (4-CHLOROPHENYL)-METHYL|-2,2-DIMETHYLCYCLOPENTANONE | KUREHA CORP (JP) | 2006-10-18 | — | — | EP | disclosed |
| CN-1196665-C | Preparation method of 5- [ (4-chlorphenyl) methyl ] -2, 2-dimethyl cyclopentanone | KUREHA CHEMICAL IND CO LTD (JP) | 2005-04-13 | — | — | CN | disclosed |
| EP-1308432-A4 | PROCESS FOR THE PREPARATION OF 5- (4-CHLOROPHENYL)-METHYL]-2,2-DIMETHYLCYCLOPENTANONE | KUREHA CHEMICAL IND CO LTD (JP) | 2004-05-12 | — | — | EP | disclosed |
| WO-2001012580-A1 | PROCESS FOR THE PREPARATION OF 5-[(4-CHLOROPHENYL)-METHYL]-2,2-DIMETHYLCYCLOPENTANONE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-02-22 | — | — | WO | disclosed |
| EP-0731083-A1 | Process for the producing of alkylcyclopentanone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140113815-A1 | AZOLE DERIVATIVE, METHOD FOR PRODUCING AZOLE DERIVATIVE, AND INTERMEDIATE COMPOUND | CBR3, CYP4F3, CYP4F11 | POLB 4241/4885SSTR1 1267/4885SSTR4 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.