Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21070970 | 1.00 | CYP2C19 (0.45) | CYP2C19RIPK1HDAC4HDAC6MEN1 | |
| SCHEMBL18528419 | 0.82 | CES1 (0.44) | CYP2C19RIPK1HDAC4HDAC6MEN1 | |
| SCHEMBL15722067 | 0.82 | MMP8 (0.48) | RIPK1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL16932333 | 0.81 | MME (0.52) | RIPK1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL15490150 | 0.80 | TSHR (0.46) | CYP2C19RIPK1HDAC4HDAC6MEN1 | |
| SCHEMBL19040090 | 0.79 | CYP2C19 (0.45) | CYP2C19RIPK1HDAC4HDAC6NPC1 | |
| SCHEMBL16878364 | 0.77 | NR1H2 (0.43) | CYP2C19RIPK1HDAC4HDAC6MEN1 | |
| SCHEMBL15688876 | 0.77 | NR1H2 (0.46) | CYP2C19RIPK1HDAC4HDAC6MEN1 | |
| SCHEMBL2562018 | 0.77 | RIPK1 (0.50) | RIPK1MEN1HTTKMT2AL3MBTL1 | |
| SCHEMBL6472726 | 0.76 | SMN1; SMN2 (0.53) | CYP2C19LMNARECQLCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034176-B2 | Aminopropylphosphinic acids | ASTRAZENECA AB (SE) | 2006-04-25 | — | — | US | claimed |