⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946415 | 0.75 | — | — | |
| SCHEMBL3132584 | 0.72 | — | — | |
| SCHEMBL13132078 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL11281865 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL9714454 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL11224392 | 0.71 | ALDH1A1 (0.31) | — | |
| SCHEMBL11226618 | 0.71 | EPHX2 (0.34) | — | |
| SCHEMBL3869824 | 0.69 | — | — | |
| SCHEMBL492511 | 0.69 | — | — | |
| SCHEMBL2992564 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7057062-B2 | Process for manufacturing purified phosphorodiamidite | ISIS PHARMACEUTICALS, INC. (US) | 2006-06-06 | — | — | US | disclosed |
| US-20030225284-A1 | Process for manufacturing purified phosphorodiamidite | IONIS PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |