Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318451 | 0.87 | EGFR (0.40) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL6053448 | 0.87 | PRMT1 (0.41) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL10936707 | 0.84 | GLA (0.53) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL30487695 | 0.82 | KDM4E (0.42) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL29757308 | 0.82 | KDM4E (0.45) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL3641661 | 0.82 | KDM4E (0.45) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL360477 | 0.81 | CYP2C19 (0.54) | EGFRALDH1A1KDM4EGLATSHR | |
| SCHEMBL359097 | 0.81 | HIF1A (0.41) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL18359692 | 0.81 | ALDH1A1 (0.48) | EGFRERBB2ALDH1A1KDM4EGAA | |
| SCHEMBL15221008 | 0.80 | GLA (0.40) | EGFRERBB2ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370591-B1 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | UNIV RAMOT (IL) | 2006-08-02 | — | — | EP | claimed |
| EP-1370591-A4 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | UNIV RAMOT (IL) | 2004-04-21 | — | — | EP | claimed |
| US-6686490-B1 | NON-METALLOCENE PRE- CATALYST FEATURING A DIAMINE DIPHENOLATE COMPLEX | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2004-02-03 | — | — | US | claimed |
| EP-1370591-A2 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | Ramot at Tel Aviv University Ltd. (IL) | 2003-12-17 | — | — | EP | claimed |
| US-6632899-B2 | Contains a diamine diphenolate complex and an activating co-catalyst | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2003-10-14 | — | — | US | claimed |
| US-20020173604-A1 | Active non-metallocene pre-catalyst and method for tactic catalytic polymerization of alpha-olefin monomers | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2002-11-21 | — | — | US | claimed |
| WO-2002036638-A2 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2002-05-10 | — | — | WO | claimed |
| US-20220118379-A1 | Separation of Radiometals | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2022-04-21 | — | — | US | disclosed |
| WO-2020030659-A1 | SEPARATION OF RADIOMETALS | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2020-02-13 | — | — | WO | disclosed |
| US-20150087795-A1 | LIGANDS DESIGNED TO PROVIDE HIGHLY ACTIVE CATALYST COMPLEXES | CARNEGIE MELLON UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
| EP-1370591-B1 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | UNIV RAMOT (IL) | 2006-08-02 | — | — | EP | disclosed |
| EP-1370591-A4 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | UNIV RAMOT (IL) | 2004-04-21 | — | — | EP | disclosed |
| US-6686490-B1 | NON-METALLOCENE PRE- CATALYST FEATURING A DIAMINE DIPHENOLATE COMPLEX | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2004-02-03 | — | — | US | disclosed |
| EP-1370591-A2 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | Ramot at Tel Aviv University Ltd. (IL) | 2003-12-17 | — | — | EP | disclosed |
| US-6632899-B2 | Contains a diamine diphenolate complex and an activating co-catalyst | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2003-10-14 | — | — | US | disclosed |
| US-20020173604-A1 | Active non-metallocene pre-catalyst and method for tactic catalytic polymerization of alpha-olefin monomers | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2002-11-21 | — | — | US | disclosed |
| WO-2002036638-A2 | ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118379-A1 | Separation of Radiometals | SLC39A3, SLC30A6, SLC39A14 | EGFR 271/4885ERBB2 2022/4885ALDH1A1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.