SCHEMBL6053448

SCHEMBL6053448

CNCCN(C)Cc1cc(C)cc(C)c1O

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 9/20 0.41
CARM1 Q86X55 9/20 0.41
EGFR P00533 4/20 0.39
ERBB2 P04626 3/20 0.39
KDM1A O60341 1/20 0.37
MOK Q9UQ07 1/20 0.35
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
SHBG P04278 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053403 0.87 EGFR (0.41) EGFRERBB2GLATSHRALOX12
SCHEMBL22828170 0.79 PRMT1 (0.50) PRMT1CARM1KDM1AMOKSIGMAR1
SCHEMBL13318451 0.78 EGFR (0.40) EGFRERBB2GLATSHRALOX12
SCHEMBL6053760 0.78 MAPT (0.41) PRMT1CARM1KDM1AMOKTSHR
SCHEMBL10936707 0.76 GLA (0.53) EGFRERBB2GLATSHRALOX12
SCHEMBL21773394 0.75 PRMT1 (0.40) PRMT1CARM1KDM1AMOK
SCHEMBL30487695 0.74 KDM4E (0.42) EGFRERBB2GLATSHRALOX12
SCHEMBL29757308 0.74 KDM4E (0.45) EGFRERBB2GLATSHRALOX12
SCHEMBL3641661 0.74 KDM4E (0.45) EGFRERBB2GLATSHRALOX12
SCHEMBL18359692 0.73 ALDH1A1 (0.48) EGFRERBB2GLATSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1370591-B1 ACTIVE NON-METALLOCENE PRE-CATALYST AND METHOD FOR TACTIC CATALYTIC POLYMERIZATION OF ALPHA-OLEFIN MONOMERS UNIV RAMOT (IL) 2006-08-02 EP claimed