SCHEMBL6054496

SCHEMBL6054496

C=CCN1CCCCC1Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.42
HTR1A P08908 3/20 0.38
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
CHRM2 P08172 1/20 0.36
ACHE P22303 1/20 0.36
PTGS1 P23219 1/20 0.36
OPRM1 P35372 1/20 0.36
DRD3 P35462 1/20 0.36
OPRK1 P41145 1/20 0.36
KCNH2 Q12809 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9276947 0.89 HTR1A (0.43) PRCPHTR1A
SCHEMBL4322788 0.80 MEN1 (0.39)
SCHEMBL9286439 0.77 PRCP (0.37) PRCPHTR1A
SCHEMBL11038501 0.77 SCN1A (0.46) PRCPCHRM2
SCHEMBL7246918 0.75 CARM1 (0.40) ACHE
SCHEMBL4341158 0.74 PRCP (0.48) PRCPHTR1AALDH1A1
SCHEMBL1751084 0.74 HRH3 (0.40) ALDH1A1DRD3
SCHEMBL7398553 0.73 KCNH2 (0.43) KCNH2
SCHEMBL11170273 0.73 CHRNB4 (0.46) KCNH2
Hydrochloric Acid SCHEMBL7398909 0.72 KCNH2 (0.42) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6211839-A None JP disclosed
US-20060257852-A1 Severe acute respiratory syndrome coronavirus CHIRON CORPORATION (US) 2006-11-16 US disclosed
CN-1829736-A severe acute respiratory syndrome coronavirus CHIRON CORP (US) 2006-09-06 CN disclosed
EP-0605031-B1 Phenoxy- and phenoxyalkyl-piperidines as antiviral agents SANOFI SA (FR) 1997-07-16 EP disclosed
US-5364865-A Phenoxy- and phenoxyalkyl-piperidines as antiviral agents STERLING WINTHROP INC. (US) 1994-11-15 US disclosed
JP-H06211839-A PHENOXY-AND PHENOXYALKYL-PIPERIDINES AS ANTIVIRAL AGENTS STERLING WINTHROP INC 1994-08-02 JP disclosed
EP-0605031-A1 Phenoxy- and phenoxyalkyl-piperidines as antiviral agents STERLING WINTHROP INC. (US) 1994-07-06 EP disclosed
EP-0103252-A2 Aryloxyalkyl amines, process for their preparation and their use in combating unwanted plant growth BASF Aktiengesellschaft (DE) 1984-03-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060257852-A1 Severe acute respiratory syndrome coronavirus SARS1, ACE2, ACE PRCP 713/4885HTR1A 3788/4885ALDH1A1 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.