Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26135660 | 0.83 | SCN1A (0.49) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL9393233 | 0.77 | NPSR1 (0.48) | MEN1KMT2ACHRNA7CHRNB2CHRNA5 | |
| SCHEMBL6054496 | 0.77 | PRCP (0.42) | CHRM2PRCP | |
| SCHEMBL11124160 | 0.76 | CHRNB2 (0.49) | MEN1KMT2ACARM1PRMT6CHRNB2 | |
| SCHEMBL14382904 | 0.76 | SLC6A1 (0.42) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL8683051 | 0.72 | ALDH1A1 (0.51) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL3262478 | 0.72 | SLC6A9 (0.43) | MEN1KMT2AOPRD1 | |
| SCHEMBL1795967 | 0.69 | LMNA (0.43) | OPRD1PRCP | |
| SCHEMBL1795969 | 0.69 | LMNA (0.43) | OPRD1PRCP | |
| SCHEMBL3780879 | 0.69 | HTT (0.48) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116255-A3 | TREATMENT OF MIGRAINE WITH N-ALKYL-PIPERIDINYL BENZOATE DERIVATIVES | MERRELL DOW FRANCE ET CIE (FR) | 1985-11-06 | — | — | EP | disclosed |
| EP-0116255-A2 | Treatment of migraine with N-alkyl-piperidinyl benzoate derivatives | MERRELL DOW FRANCE ET CIE (FR) | 1984-08-22 | — | — | EP | disclosed |
| EP-0116255-A2 | Treatment of migraine with N-alkyl-piperidinyl benzoate derivatives | MERRELL DOW FRANCE ET CIE (FR) | 1984-08-22 | — | — | EP | disclosed |