Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | HTR2B | P41595 | 4/20 | 0.53 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28152000 | 0.99 | GID4 (0.53) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL1931841 | 0.86 | PRCP (0.53) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL6404152 | 0.86 | PRCP (0.53) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL6405760 | 0.86 | PRCP (0.53) | GID4HTR2CHTR2BSCN4AKDM4E | |
| Hydrochloric Acid SCHEMBL6432085 | 0.84 | PRCP (0.51) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL7996653 | 0.81 | GID4 (0.72) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL7996650 | 0.81 | GID4 (0.72) | GID4HTR2CHTR2BSCN4AKDM4E | |
| SCHEMBL22221105 | 0.80 | HTR2C (0.68) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL9469302 | 0.79 | HTR2C (0.71) | GID4HTR2CHTR2BKDM4E | |
| SCHEMBL3261012 | 0.79 | EPHX1 (0.51) | GID4SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504004-A1 | PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC APPLICATIONS OF A HYDROCORTISONE DERIVATIVE DESIGNATED AS DEINA | Barco, Giovanni (IT) | 2012-10-03 | — | — | EP | disclosed |
| WO-2006012700-A1 | METHOD OF TREATMENT | TEAM HEALTH PTY LTD (AU) | 2006-02-09 | — | — | WO | disclosed |
| EP-1539181-A4 | METHOD OF TREATING LOWER URINARY TRACT DISORDERS | DYNOGEN PHARMACEUTICALS INC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005117872-A2 | DUAL ACTING SNRI-NMDA ANTAGONISTS FOR THE TREATMENT OF GENITOURINARY DISORDERS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1596844-A2 | USE OF SODIUM CHANNEL MODULATORS FOR TREATING GASTROINTESTINAL TRACT DISORDERS | Dynogen Pharmaceuticals Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| EP-1589959-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | Dynogen Pharmaceuticals Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1539181-A2 | METHOD OF TREATING LOWER URINARY TRACT DISORDERS | Dynogen Pharmaceuticals Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004089288-A2 | METHOD OF TREATING LOWER URINARY TRACT DISORDERS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-10-21 | — | — | WO | disclosed |
| WO-2004066990-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004066987-A2 | USE OF SODIUM CHANNEL MODULATORS FOR TREATING GASTROINTESTINAL TRACT DISORDERS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |
| EP-1158978-A4 | MEDICAMENT AGAINST DYSMENORRHOEA AND PREMENSTRUAL SYNDROME | EDELSTAM INC (US) | 2004-03-17 | — | — | EP | disclosed |
| EP-1158978-A1 | MEDICAMENT AGAINST DYSMENORRHOEA AND PREMENSTRUAL SYNDROME | Edelstam Inc. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000053183-A1 | MEDICAMENT AGAINST DYSMENORRHOEA AND PREMENSTRUAL SYNDROME | EDELSTAM INC. (US) | 2000-09-14 | — | — | WO | disclosed |