Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.72 |
| ▸ | HTR2C | P28335 | 6/20 | 0.54 |
| ▸ | HTR2B | P41595 | 4/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996653 | 1.00 | GID4 (0.72) | GID4HTR2CHTR2BP2RX7KDM4E | |
| SCHEMBL18019717 | 0.84 | PKM (0.57) | GID4HTR2CHTR2BP2RX7HPGD | |
| SCHEMBL8304059 | 0.82 | HTR2C (0.55) | GID4HTR2CHTR2BP2RX7KDM4E | |
| SCHEMBL8304057 | 0.82 | HTR2C (0.55) | GID4HTR2CHTR2BP2RX7KDM4E | |
| SCHEMBL3855999 | 0.81 | GID4 (0.54) | GID4HTR2CHTR2BKDM4EHPGD | |
| SCHEMBL3856002 | 0.81 | GID4 (0.54) | GID4HTR2CHTR2BKDM4EHPGD | |
| SCHEMBL6054528 | 0.81 | GID4 (0.54) | GID4HTR2CHTR2BP2RX7KDM4E | |
| SCHEMBL27818505 | 0.81 | GID4 (0.56) | GID4HTR2CHTR2BP2RX7KMT2A | |
| SCHEMBL5154669 | 0.80 | HTR2C (0.77) | GID4HTR2CHTR2BKDM4EHPGD | |
| SCHEMBL1789145 | 0.80 | HTR2C (0.77) | GID4HTR2CHTR2BKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291432-B1 | (R)-N-(2-METHYLBENZYL)-3-((2S, 3S)-3-(N-(2-CHROMONECARBONYL)-L-ASPARAGINYL)AMINO-2-HYDROXY-4-PHENYLBUTANO YL)-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXAMIDE CAN BE GIVEN AS A TYPICAL EXAMPLE OF THIS COMPOUND. | JAPAN ENERGY CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0900566-A1 | NOVEL TRIPEPTIDE COMPOUNDS AND ANTI-AIDS DRUGS | JAPAN ENERGY CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |