Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 4/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054929 | 0.81 | FYN (0.36) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL9559840 | 0.81 | NQO1 (0.56) | MEN1KMT2ANQO1 | |
| SCHEMBL8376520 | 0.80 | NQO1 (0.37) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL7522755 | 0.80 | CA1 (0.48) | MEN1KMT2A | |
| SCHEMBL23803509 | 0.77 | MMP2 (0.35) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL15112970 | 0.77 | FYN (0.37) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL3589633 | 0.77 | NQO1 (0.50) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL19755181 | 0.75 | FYN (0.38) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL10276399 | 0.75 | FYN (0.38) | FYNMMP2MMP3MMP9MMP14 | |
| SCHEMBL7888513 | 0.73 | MEN1 (0.36) | FYNMMP2MMP3MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677804-A1 | SILYL PHENOLS FOR PROMOTING VASCULAR HEALTH | Amylin Pharmaceuticals, Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005039596-A1 | SILYL PHENOLS FOR PROMOTING VASCULAR HEALTH | AMYLIN PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |