Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431727 | 0.89 | TDP1 (0.33) | TDP1 | |
| SCHEMBL6443475 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL5274910 | 0.76 | TSHR (0.33) | TDP1 | |
| SCHEMBL9958869 | 0.76 | — | — | |
| SCHEMBL1815773 | 0.74 | TDP1 (0.65) | TDP1 | |
| SCHEMBL3422323 | 0.74 | TDP1 (0.65) | TDP1 | |
| SCHEMBL10510379 | 0.72 | TDP1 (0.33) | TDP1 | |
| SCHEMBL10511703 | 0.72 | TDP1 (0.33) | TDP1 | |
| SCHEMBL3477908 | 0.72 | TDP1 (0.33) | TDP1 | |
| SCHEMBL10511428 | 0.72 | TDP1 (0.33) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006111355-A1 | COMPOSITIONS FOR THE PREVENTION AND THE TREATMENT OF PAIN COMPRISING PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN (PEBP) DERIVED MOLECULES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2006-10-26 | — | — | WO | disclosed |
| US-6693179-B2 | GENERATION OF MORPHINE-6-GLUCURONIDE; OBTAIN CHEMICAL INTERMEDIATES, INCUBATE IN REACTION MIXTURE, RECOVER MORPHINE-6-GLUCURONIDE | CENES LIMITED (GB) | 2004-02-17 | — | — | US | disclosed |
| US-6566510-B1 | Generation of preferential glycosides; obtain chemical intermediates, incubate with reation mixture, recover glycosides | GENES LIMITED (GB) | 2003-05-20 | — | — | US | disclosed |
| EP-1086114-B1 | MORPHINE-6-GLUCURONIDE SYNTHESIS | CENES LTD (GB) | 2002-10-02 | — | — | EP | disclosed |