Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055552 | 0.79 | MAPT (0.40) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1071467 | 0.76 | MAPT (0.37) | MAPTKDM4ETDP1KMT2AMEN1 | |
| SCHEMBL26134606 | 0.73 | CCR1 (0.35) | MAPTKDM4ETDP1KMT2AMEN1 | |
| SCHEMBL6131341 | 0.71 | KDM4E (0.38) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4452823 | 0.68 | MAPT (0.38) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1071823 | 0.68 | MAPT (0.37) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1685838 | 0.66 | ESR1 (0.35) | MAPTKDM4ETDP1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL1072266 | 0.66 | PSMD14 (0.37) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1070024 | 0.65 | MAPT (0.36) | MAPTKDM4ETDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1072411 | 0.64 | MAPT (0.39) | MAPTKDM4ETDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919412-B1 | Monocyclopentadienyl complexes of chromium, molybdenum or tungsten with a donor bridge | BASELL POLYOLEFINE GMBH (DE) | 2005-07-19 | — | — | US | disclosed |