SCHEMBL60563

SCHEMBL60563

CCCCCOc1cc[c]cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.57
LTA4H P09960 5/20 0.55
TP53 P04637 2/20 0.50
TSHR P16473 2/20 0.50
PLA2G4B P0C869 1/20 0.49
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
RARB P10826 3/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1611001 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL988767 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL659360 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL987954 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL77477 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL263776 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL338316 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL309133 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL9121701 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL1609987 0.98 NR5A1 (0.60) NR5A1LTA4HTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2355 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124419-A1 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-04-18 US claimed
EP-4288416-A2 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF The Regents Of The University Of Michigan (US) 2023-12-13 EP claimed
US-20230233536-A1 RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA QURETECH BIO AB (SE) 2023-07-27 US claimed
CN-116178197-A (Z) -N-substituted enaminone derivative, preparation method and application thereof 浙江医药股份有限公司新昌制药厂 2023-05-30 CN claimed
CN-115368422-A 4', 11-O- (1, 2, 3-triazole) clarithromycin derivatives, and preparation method and application thereof 河南省人民医院 2022-11-22 CN claimed
WO-2022169834-A2 SMALL MOLECULE INHIBITORS OF GRP78 AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2022-08-11 WO claimed
CN-114478500-A Coumarin two-photon initiator and synthesis method and application thereof 浙江大学 2022-05-13 CN claimed
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN claimed
CN-114206886-A Luminescent gold (III) compound, method for preparing same, and organic light emitting device using same 广东聚华印刷显示技术有限公司 2022-03-18 CN claimed
CN-114057625-A C2-acyloxy-3-indolinone derivative and preparation method and application thereof 五邑大学 2022-02-18 CN claimed
EP-0033947-B2 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1987-01-14 EP claimed
EP-0065978-B1 NOVEL YELLOW AZO DYES AND DICHROIC LIQUID CRYSTAL COMPOSITIONS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 1985-09-04 EP claimed
EP-0033947-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1983-09-21 EP claimed
EP-0065978-A4 NOVEL YELLOW AZO DYES AND DICHROIC LIQUID CRYSTAL COMPOSITIONS MADE THEREFROM. GEN ELECTRIC (US) 1983-04-18 EP claimed
EP-0065978-A1 NOVEL YELLOW AZO DYES AND DICHROIC LIQUID CRYSTAL COMPOSITIONS MADE THEREFROM. GEN ELECTRIC (US) 1982-12-08 EP claimed
WO-1982002054-A1 NOVEL YELLOW AZO DYES AND DICHROIC LIQUID CRYSTAL COMPOSITIONS MADE THEREFROM GEN ELECTRIC (US) 1982-06-24 WO claimed
US-4323567-A BACTERICIDES NARISADA MASAYUKI 1982-04-06 US claimed
US-4308162-A Novel yellow azo dyes and dichroic liquid crystal compositions made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 US claimed
US-4138486-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1979-02-06 US claimed
US-4001137-A Nematic compounds and mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-01-04 US claimed