Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6056332 | 0.88 | MAPK1 (0.44) | MAPK1SMN1; SMN2HTTGAAEPHX2 | |
| SCHEMBL6056303 | 0.88 | PPARG (0.44) | MAPK1PPARDPPARASMN1; SMN2HTT | |
| SCHEMBL6056315 | 0.87 | PPARA (0.50) | MAPK1PPARAHTTGAAEPHX2 | |
| SCHEMBL6056262 | 0.85 | PPARG (0.41) | PPARA | |
| SCHEMBL21245515 | 0.83 | ALDH1A1 (0.48) | KDM4EGAATDP1 | |
| SCHEMBL6056264 | 0.82 | KDM4E (0.46) | PPARAKDM4EHTTGAATDP1 | |
| SCHEMBL6056240 | 0.79 | ALDH1A1 (0.48) | MAPK1PPARAKDM4ETDP1 | |
| SCHEMBL6056319 | 0.78 | KDM4E (0.49) | PPARDPPARAKDM4EHTT | |
| SCHEMBL21245496 | 0.77 | KDM4E (0.51) | PPARDPPARAKDM4EHTTGAA | |
| SCHEMBL6056250 | 0.77 | MEN1 (0.44) | PPARDPPARASMN1; SMN2HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675582-A1 | COMBINATION COMPRISING AN ALPHA-2-DELTA LIGAND AND AN SSRI AND/OR SNRI FOR TREATMENT OF DEPRESSION AND ANXIETY DISORDERS | Warner-Lambert Company LLC (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005025563-A1 | COMBINATION COMPRISING AN ALPHA-2-DELTA LIGAND AND AN SSRI AND/OR SNRI FOR TREATMENT OF DEPRESSION AND ANXIETY DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |