SCHEMBL6056743

SCHEMBL6056743

COC(C/C(C(=O)O)=C(\CC(OC)OC)C(=O)O)OC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
HTT P42858 1/20 0.39
RECQL P46063 1/20 0.39
GRIK1 P39086 2/20 0.37
GRIA4 P48058 1/20 0.34
GRIK3 Q13003 1/20 0.34
GRIK5 Q16478 1/20 0.34
NPC1 O15118 1/20 0.34
KMT2A Q03164 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
MMP12 P39900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL607414 0.78
SCHEMBL3622300 0.77 GRIK1 (0.35) GRIK1GRIA4GRIK3GRIK5KMT2A
SCHEMBL4408191 0.76 SLC22A6 (0.41) GAAHTTRECQLMAPTMMP12
SCHEMBL8022411 0.75 TET2 (0.48) GAAHTTRECQLGRIK1
SCHEMBL3238307 0.75 GAA (0.34) GAAHTTRECQLNPC1L3MBTL1
SCHEMBL122205 0.72
SCHEMBL322299 0.70
SCHEMBL28378728 0.70 ALDH1A1 (0.38) GAAHTTRECQLL3MBTL1
SCHEMBL342829 0.70
SCHEMBL99435 0.70 TSHR (0.48) GAAHTTRECQLKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006007917-A1 COMPOSITION OF FLUORINATED SILICONES, PARTICULARLY BUT NOT EXCLUSIVELY FOR ADHESIVE-RELEASING COATINGS, AND PREPARATION THEREOF MAFLON S.R.L. (IT) 2006-01-26 WO claimed
WO-2006007917-A1 COMPOSITION OF FLUORINATED SILICONES, PARTICULARLY BUT NOT EXCLUSIVELY FOR ADHESIVE-RELEASING COATINGS, AND PREPARATION THEREOF MAFLON S.R.L. (IT) 2006-01-26 WO disclosed