SCHEMBL6057230

SCHEMBL6057230

CC(C)COC(=O)c1ccccc1Cl

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.77
TSHR P16473 3/20 0.77
ADRB2 P07550 3/20 0.65
ADRB1 P08588 3/20 0.65
ADRB3 P13945 3/20 0.65
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
TP53 P04637 1/20 0.52
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
KMT2A Q03164 1/20 0.52
ATM Q13315 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
KDM4E B2RXH2 1/20 0.50
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946893 0.94 ALDH1A1 (0.68) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL8144263 0.87 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL42787 0.87 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL29387332 0.87 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
Ammonia Solution, Strong SCHEMBL28046886 0.85 ALDH1A1 (0.96) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL27345462 0.85 ALDH1A1 (0.96) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL27494884 0.85 ALDH1A1 (0.96) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL4625826 0.85 ALDH1A1 (0.65) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL9463946 0.84 ADRB2 (0.71) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL15770393 0.84 ALDH1A1 (0.63) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109693176-A Polishing layer, polishing pad and preparation method 湖北鼎汇微电子材料有限公司 2019-04-30 CN claimed
US-5380910-A Dehalogeno coupling IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-10 US claimed
CN-117957021-A Process for preparing pegylated adrenomedullin, intermediates therefor and uses thereof 拜耳公司 2024-04-30 CN disclosed
CN-109693176-A Polishing layer, polishing pad and preparation method 湖北鼎汇微电子材料有限公司 2019-04-30 CN disclosed
CN-109554101-A A kind of polyurethane water-proof paint 唐山东方雨虹防水技术有限责任公司 2019-04-02 CN disclosed
CN-109438644-A A kind of preparation method of high-tension polyurethane 张海军 2019-03-08 CN disclosed
EP-1159315-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
EP-1192196-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-07-13 EP disclosed
EP-1183284-B1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEM CO (US) 2005-04-27 EP disclosed
CN-1196719-C Procatalysts including bidentate ligands, catalyst systems and their use in olefin polymerization EASTMAN CHEM CO (US) 2005-04-13 CN disclosed
CN-1144821-C Procatalysts comprising bidentate ligands, catalyst systems, and use in olefin polymerization 伊斯曼化学公司 2004-04-07 CN disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
US-6271321-B1 CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY 2001-08-07 US disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed
EP-0571770-B1 Method for producing an asymmetric biaryl derivative IHARA CHEMICAL IND CO (JP) 1996-07-10 EP disclosed
US-5380910-A Dehalogeno coupling IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-10 US disclosed
EP-0571770-A1 Method for producing an asymmetric biaryl derivative IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1993-12-01 EP disclosed