SCHEMBL6057368

SCHEMBL6057368

CCCOC(=O)c1cccc(Cl)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
ALDH1A1 P00352 6/20 0.56
CHRM1 P11229 2/20 0.56
CHRM2 P08172 1/20 0.56
CHRM4 P08173 1/20 0.56
CHRM3 P20309 1/20 0.56
ESR1 P03372 1/20 0.53
TSHR P16473 1/20 0.53
SLC6A2 P23975 1/20 0.53
KDR P35968 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
RAB9A P51151 1/20 0.52
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
PFKFB3 Q16875 1/20 0.51
PFKFB4 Q16877 1/20 0.51
ADORA3 P0DMS8 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27428199 0.94 LMNA (0.57) LMNAALDH1A1CHRM1CHRM2CHRM4
SCHEMBL7471813 0.94 LMNA (0.57) LMNAALDH1A1CHRM1CHRM2CHRM4
SCHEMBL14335520 0.91 LMNA (0.53) LMNAALDH1A1CHRM1CHRM2CHRM4
SCHEMBL198523 0.90 ESR1 (0.59) LMNAALDH1A1CHRM1CHRM2CHRM4
SCHEMBL810821 0.90 L3MBTL1 (0.57) ALDH1A1CHRM1CHRM2CHRM4CHRM3
SCHEMBL6057136 0.89 LMNA (0.56) LMNAALDH1A1ESR1TSHRTDP1
Ammonia Solution, Strong SCHEMBL10348735 0.89 ESR1 (0.57) LMNAALDH1A1CHRM1CHRM2CHRM4
Hydrogen Peroxide SCHEMBL27761851 0.89 ESR1 (0.57) LMNAALDH1A1CHRM1CHRM2CHRM4
SCHEMBL28437780 0.88 LMNA (0.58) LMNAALDH1A1ESR1TSHRTDP1
SCHEMBL30692290 0.88 LMNA (0.58) LMNAALDH1A1ESR1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN claimed
CN-107580607-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-09-27 CN disclosed
CN-103781805-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限责任公司 2016-10-12 CN disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN disclosed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN disclosed
WO-2012147107-A2 NOVEL & IMPROVED PROCESSES FOR THE PREPARATION OF INDOLINE DERIVATIVES AND ITS PHARMACEUTICAL COMPOSITION MSN LABORATORIES LIMITED (IN) 2012-11-01 WO disclosed
EP-1159315-B1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEM CO (US) 2006-09-06 EP disclosed
CN-1214049-C Process for producing ethylene/olefin interpolymers EASTMAN CHEM CO (US) 2005-08-10 CN disclosed
EP-1159315-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010029286-A1 Procatalysts, catalyst systems, and use in OLEFIN polymerization EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE 2001-10-11 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
US-6271321-B1 CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY 2001-08-07 US disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000052068-A1 PROCESS FOR PRODUCING POLYETHYLENE EASTMAN CHEMICAL COMPANY (US) 2000-09-08 WO disclosed