SCHEMBL6057404

SCHEMBL6057404

Cc1ccc(OP(=O)(O)Cl)c(-c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 0.55
GPR84 Q9NQS5 1/20 0.51
HDAC7 Q8WUI4 1/20 0.47
MAOB P27338 1/20 0.39
PSMB5 P28074 1/20 0.39
CHRM3 P20309 4/20 0.37
HPRT1 P00492 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
PTPN5 P54829 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
HTT P42858 1/20 0.36
ACP3 P15309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518516 0.88 PTGDR2 (0.57) PTGDR2GPR84HDAC7MAOBHPRT1
SCHEMBL3886720 0.86 PTGDR2 (0.56) PTGDR2GPR84HDAC7MAOBPSMB5
SCHEMBL4127831 0.84 PTGDR2 (0.54) PTGDR2GPR84HDAC7MAOBPSMB5
SCHEMBL4127048 0.82 PTGDR2 (0.56) PTGDR2GPR84HDAC7CHRM3L3MBTL1
SCHEMBL4127148 0.82 PTGDR2 (0.52) PTGDR2GPR84HDAC7MAOBHPRT1
SCHEMBL3883343 0.81 PTGDR2 (0.55) PTGDR2GPR84HDAC7MAOBCHRM3
SCHEMBL3116257 0.80 GPR84 (0.51) GPR84L3MBTL1LMNAMAPK1TDP1
SCHEMBL4135115 0.80 PTGDR2 (0.50) PTGDR2GPR84HDAC7HPRT1L3MBTL1
Phosphoric Acid SCHEMBL29381893 0.79 PTGDR2 (0.55) PTGDR2GPR84HDAC7L3MBTL1LMNA
Phosphoric Acid SCHEMBL35596 0.79 PTGDR2 (0.55) PTGDR2GPR84HDAC7L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed