Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 17/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058429 | 0.90 | LCK (0.61) | LCK | |
| SCHEMBL7452674 | 0.82 | RAB9A (0.65) | LMNAMAPT | |
| SCHEMBL6057945 | 0.81 | LCK (0.56) | LCK | |
| SCHEMBL7626000 | 0.78 | NPC1 (0.62) | LCKLMNAMAPT | |
| SCHEMBL6058329 | 0.78 | LCK (0.54) | LCK | |
| SCHEMBL6057832 | 0.78 | LCK (0.79) | LCKFYNSRC | |
| SCHEMBL7456062 | 0.76 | GFER (0.62) | TP53LMNAMAPT | |
| SCHEMBL6058160 | 0.76 | LCK (0.82) | LCKTP53LMNAMAPT | |
| SCHEMBL7258260 | 0.74 | RAB9A (0.54) | TP53LMNAMAPT | |
| SCHEMBL3053748 | 0.74 | PIK3CA (0.51) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037632-B1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-01-11 | — | — | EP | claimed |