SCHEMBL6058375

SCHEMBL6058375

OC(Cl)C(Cl)(Cl)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8462964 0.74
SCHEMBL11822697 0.74
SCHEMBL11843692 0.73 LMNA (0.33) LMNAALDH1A1HSD17B10
SCHEMBL3968292 0.72 LMNA (0.38) LMNA
SCHEMBL1993226 0.72 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL1316837 0.70
SCHEMBL225312 0.69 ALDH1A1 (0.32) ALDH1A1HSD17B10
SCHEMBL27990990 0.67
SCHEMBL9859427 0.67 ALDH1A1 (0.37) ALDH1A1HSD17B10
SCHEMBL20710005 0.67 ALDH1A1 (0.30) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1241227-B1 Additives for hydrogenated resins SOLVAY SOLEXIS SPA (IT) 2006-02-22 EP disclosed
US-6936654-B2 Additives for hydrogenated resins AUSIMONT, S.P.A. (IT) 2005-08-30 US disclosed
US-20040102575-A1 Additives for hydrogenated resins AUSIMONT S.P.A. 2004-05-27 US disclosed
US-6683128-B2 OBTAINABLE USING BIFUNCTIONAL PERFLUOROPOLYETHERS HAVING -COOR END GROUP, MONO OR POLYFUNCTIONAL HYDROGENATED MONOMERS HAVING FUNCTIONAL GROUPS REACTIVE WITH -COOR END GROUPS OF FIRST COMPOUND, POLYOLEFINS HAVING GROUPS REACTIVE WITH -COOR GROUPS AUSIMONT S.P.A. (IT) 2004-01-27 US disclosed
US-20020177651-A1 Additives for hydrogenated resins AUSIMONT S.P.A. 2002-11-28 US disclosed
EP-1241227-A1 Additives for hydrogenated resins Ausimont S.p.A. (IT) 2002-09-18 EP disclosed