Pentachlorophenol

Pentachlorophenol

SCHEMBL6058490

CCC(O)F.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
CYP1A2 P05177 4/20 0.50
CYP2C9 P11712 4/20 0.50
HIF1A Q16665 3/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.40
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL7922521 0.78 TSHR (0.62) TSHRCYP1A2CYP2C9HIF1AHPGD
Pentachlorophenol SCHEMBL18525333 0.75 TSHR (0.67) TSHRCYP1A2CYP2C9HIF1AHPGD
Pentachlorophenol SCHEMBL10336353 0.75 TSHR (0.67) TSHRCYP1A2CYP2C9HIF1AHPGD
SCHEMBL868502 0.74
SCHEMBL868160 0.74
SCHEMBL513925 0.74
Pentachlorophenol SCHEMBL27689241 0.74 TSHR (0.56) TSHRCYP1A2CYP2C9HIF1AHPGD
Pentachlorophenol SCHEMBL18039457 0.73 CYP1A2 (0.48) TSHRCYP1A2CYP2C9HIF1AHPGD
Pentachlorophenol SCHEMBL10440057 0.72 CYP1A2 (0.57) TSHRCYP1A2CYP2C9HIF1AHPGD
Pentachlorophenol SCHEMBL28030118 0.71 HSD17B10 (0.83) TSHRCYP1A2CYP2C9HIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1244727-B1 MONOHYDRIC POLYFLUOROOXETANE OLIGOMERS, POLYMERS, AND COPOLYMERS AND COATINGS CONTAINING THE SAME OMNOVA SOLUTIONS INC (US) 2006-08-09 EP claimed
EP-0403962-A2 Fluorine-containing alcoholbased dehydrating agent and method of drying articles DAIKIN INDUSTRIES, LIMITED (JP) 1990-12-27 EP disclosed
EP-0389087-A2 Washing agent and method MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-09-26 EP disclosed